England make two changes to the side that beat Ireland for Sunday's fixture with Courtney Lawes replacing the injured Maro Itoje while Chris Ashton starts his first Guinness Six Nations match since 2013 in place of Jack Nowell.
Dan Cole (Leicester Tigers), Joe Launchbury (Wasps) and Ben Moon (Exeter Chiefs) are included as finishers for the first time this tournament.
France have made several changes following their opening round loss to Wales.
Mathieu Bastareaud replaces teenager Romain Ntamack while Geoffrey Doumayrou comes in for Wesley Fofana as Jacques Brunel selects a totally new midfield.
Yoann Huget switches to full-back after Maxime Medard's injury, with Gael Fickou brought in on the wing.
Demba Bamba comes in at tight-head prop for the injured Uini Atonio, while Felix Lambey and Yacouba Camara replace Paul Willemse and Wenceslas Lauret at second row and flanker.
When? Sunday 10 February
What time is kick-off? 3pm GMT
Where? Twickenham Stadium
Coverage? ITV and BBC Radio 5 live
Three to watch
Former England, Newcastle, Northampton and Toulon centre Tom May picks out three players to watch ahead of Sunday's game.
Views from the camp
England head coach Eddie Jones: "After the Ireland game we have had to refocus and reset. Players have been very good and certainly by Sunday we’ll be at our best.
"The French are always an interesting side to play against. They are full of talent, they have a lot of unpredictability so it’s hard to prepare tactically against them so we have had a real focus on ourselves."
France head coach Jacques Brunel: “Our main goal is to increase the tempo. We managed to do it in the first half against Wales and we need it to continue.
“Our difficult run of results obviously affect us, but we have to show fortitude in difficult times, and I’m sure we will make progress.
“We have not won at Twickenham for 14 years, it’s a long time. It’s always special to play these games – we know it will be close.”
2018: England 16-22 France, Stade de France
2017: England 19-16 France, Twickenham
2016: England 31-21 France, Stade de France
2015: England 55-35 France, Twickenham Stadium
2014: England 24-26 France, Stade de France
2013: England 23-13 France, Twickenham Stadium
2012: England 24-22 France, Stade de France
2011: England 17-9 France, Twickenham Stadium
- England have won nine of their last 12 Six Nations games against France (L3), however Le Bleus will be aiming for consecutive wins against England for the first time since 2006 having won 22-16 in Paris last season.
- France have managed just one win at Twickenham in the Six Nations era, a narrow 18-17 win in 2005 when Dimitri Yachvili kicked the visitors to victory with all 18 points.
- Ireland’s win at Twickenham last year ended a run of 15 consecutive home wins for England in the Six Nations, the last time they lost back to back home games in the Championship was in 1983 (vs France and Scotland).
- France have won just one of their last eight away games in the Six Nations (L7), a win against Italy in 2017, in fact their only four wins in their last 19 away games have all come in either Rome (twice) or Edinburgh (twice).
- Since the start of 2018 France have lost five of the seven games that they have led at half-time in, more than any other international side in that time; prior to this period they were undefeated in 15 consecutive matches when they had led at the break (W14, D1).
- Both England and France recorded 88% tackle success rates in the opening round of the 2019 Six Nations, however England (209) completed more than twice as many as France did (103).
- The last time England beat Ireland away from home in the Six Nations they backed it up with a 23-13 home win against France, however France had led
that game 10-9 at the break at Twickenham.
- Mark Wilson and Mako Vunipola both made 27 tackles for England in the opening round of the 2019 Six Nations, no other player in any of the three matches made more than 20 and no England player has ever made as many in a Six Nations game (Chris Robshaw 26 v Wales 2015).
- Since the start of 2018 only Rieko Ioane (New Zealand, 11) has scored more tries in international rugby than England’s Jonny May (9 tries in 12 games).
- Jonny May has scored in three consecutive Six Nations appearances, only Will Greenwood, Mark Cueto and Anthony Watson (all four consecutive games) have scored in more matches in a row in the tournament for England since 2000.
England (555 caps) - 15 Elliot Daly (Wasps, 26 caps), 14 Chris Ashton (Sale Sharks, 43 caps), 13 Henry Slade (Exeter Chiefs, 18 caps), 12 Manu Tuilagi (Leicester Tigers, 28 caps), 11 Jonny May (Leicester Tigers, 41 caps), 10 Owen Farrell (Saracens, 66 caps) (c), 9 Ben Youngs (Leicester Tigers, 81 caps), 1 Mako Vunipola (Saracens, 52 caps), 2 Jamie George (Saracens, 33 caps), 3 Kyle Sinckler (Harlequins, 18 caps), 4 Courtney Lawes (Northampton Saints, 69 caps), 5 George Kruis (Saracens, 28 caps), 6 Mark Wilson (Newcastle Falcons, 9 caps), 7 Tom Curry (Sale Sharks, 6 caps), 8 Billy Vunipola (Saracens, 37 caps).
Finishers (249 caps) 16 Luke Cowan-Dickie (Exeter Chiefs, 8 caps), 17 Ben Moon (Exeter Chiefs, 4 caps), 18 Dan Cole (Leicester Tigers, 82 caps), 19 Joe Launchbury (Wasps, 54 caps), 20 Nathan Hughes (Wasps, 19 caps), 21 Dan Robson (Wasps, uncapped), 22 George Ford (Leicester Tigers, 52 caps), 23 Jack Nowell (Exeter Chiefs, 30 caps).
France - Huget; Penaud, Doumayrou, Bastareaud, Fickou; Lopez, Parra; Poirot, Guirado, Bamba, Lambey, Vahaamahina, Camara, Iturria, Picamoles.
Replacements: Bourgarit, Priso, Aldegheri, Willemse, Alldritt, Dupont, Ntamack, Ramos.